SMASH is the reference Analog and Mixed-Signal (AMS), Logic and Mixed-Signal (LMS) and All-in-One Simulator enabling truthfully the combination of digital, logic and analog multi-domain modeling with no need for a cosimulation backplane, as well as Instruction Set Simulation (ISS). Moreover, the extensive support of design kits and foundry model parameter sets is regularly enhanced with new and emerging SPICE device model implementations (Level 49, from BSIM 3 to BSIM 4v6, EKV, ACM, MM9, VBIC, MEXTRAM, JUNCAP2, PSP).