Lixoft Monolix Suite 2018 R2 Monolix is a platform of reference for model-based drug development. It combines the most advanced algorithms with unique ease of use. Pharmacometricians and biostatisticians can rely on Monolix for population analysis and to model PK/PD and other complex biochemical and physiological processes. Monolix is an easy, fast and powerful tool for parameter estimation in non-linear mixed effect models, model diagnosis and assessment, and advanced graphical representation.