DDDPlus v5.0 DDDPlus, the industry's only in vitro dissolution software for formulation and analytical scientists, models and simulates the in vitro dissolution of active pharmaceutical ingredients (API) and formulation excipients under various experimental conditions. For new API, a single calibration experiment is all that is needed, after which DDDPlus will predict how changes in formulation or experimental parameters will affect the dissolution rate. With DDDPlus, you no longer have to rely on 'cut and try' methods to finalize a formulation design or dissolution method. New in version 5! Additional dosage forms: new models for coated beads, bilayer tablets, and delayed release coated tablets Integration of the ADMET Predictor™ Module: now predict key physicochemical properties from chemical structure Improved handling of bile salt effects on solubility in the biorelevant media Upgraded 3D Parameter Sensitivity Analysis: assess the impact of changes to any combination of formulation and experimental parameters together Various options for defining manufacturing properties: tensile strength and bonding constants can be added to predict disintegration